Twilight Zone, being an anthology series, lent itself to having different directors throughout the series. George T. Clemens being the director of photography on most of the episodes gave them the “look” to tie the series together. Having the same director on every episode may have kept the series from continuing to be fresh. Of course, this is only my opinion and I have no experience in producing a television program.
No TZs were actually shot in Binghamton. The episode that most utilizes Rod’s memories of Binghamton is “Walking Distance” with a Recreation Park setting near his hometown neighborhood. There are many hints of Binghamton in other episodes but none so blatant.